Exosomes? Another fad??

Let’s be fair as practitioners we are constantly fed BS about treatments and machines so it’s our responsibility to delve into the evidence to see whether they are what they say they are.. so let’s talk Exosomes… 

Well let’s start with understanding what they are? Exosomes are tiny extracellular vesicles that are secreted by various cells in our body, including stem cells. These microscopic packages contain a range of bioactive molecules, such as proteins, nucleic acids, and growth factors: they play a crucial role in cell-to-cell communication and have shown immense potential in regenerative medicine!! 

Exosomes have been found to possess remarkable regenerative properties that can reverse the signs of aging. When applied topically or injected into the skin, exosomes can penetrate deeply and deliver their cargo of bioactive molecules to the target cells. These molecules help stimulate cellular repair, promote collagen production, and enhance skin elasticity, resulting in smoother, firmer, and more youthful-looking skin! Too good to be true? 

One of the key factors contributing to aging skin is the decline in the regenerative capacity of our cells. Exosomes have the ability to activate dormant or aging cells, kickstarting the natural rejuvenation process. By promoting cell renewal and proliferation, exosomes can help reverse the signs of aging, including fine lines, wrinkles, and age spots.. so in essence within the science have we found the key to reversing the signs of ageing at a cellular level??

Inflammation and oxidative stress are major contributors to the aging process and our lives are full of stress! Exosomes have been shown to possess potent anti-inflammatory and antioxidant properties thus by targeting and reducing inflammation and oxidative stress in the skin, exosomes can prevent further damage and promote a more youthful appearance! Sooo… this is all sounding pretty exciting right?

But is it safe? 

One of the most appealing aspects of exosome therapy is its safety and non-invasive nature. Unlike traditional anti-aging treatments that may involve surgery or harsh chemicals, exosome therapy utilises the body's own natural regenerative mechanisms and therefore reduces the risk of adverse reactions and makes it a suitable option for individuals seeking a more natural approach to reversing the signs of aging… so managing expectations and choosing the right patient is key with Exosomes! 

Exosomes have emerged as promising tools in the field of regenerative medicine, offering a revolutionary approach to reverse the signs of aging. Through their regenerative and reparative properties, exosomes hold the potential to restore youthful vitality to aging skin.

This is just a quick taster but hopefully enough to show you there is real promise in Exosomes… get on board with it guys, you do not want to miss out.. 

Check out some great papers - 

Stem Cell Investig. 2021; 8: 7. Published online 2021 Apr 2. doi: 10.21037/sci-2020-037 PMCID: PMC8100822PMID: 33969112

Kalluri R. The biology and function of exosomes in cancer. J Clin Invest 2016;126:1208-15. 10.1172/JCI81135

Tissue Eng Regen Med. 2022 Oct; 19(5): 961–968. Published online 2022 Jul 9. doi: 10.1007/s13770-022-00461-5

Cells. 2023 Feb; 12(4): 527. Published online 2023 Feb 6. doi: 10.3390/cells12040527

PMCID: PMC9954704PMID: 36831194